Potential utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction-associated steatohepatitis.

Junyan LyuHikari OkadaHajime SunagozakaKazunori KawaguchiTetsuro ShimakamiKouki NioKazuhisa MuraiTakayoshi ShirasakiMika YoshidaKuniaki AraiTatsuya YamashitaTakuji TanakaKenichi HaradaToshinari TakamuraShuichi KanekoTaro YamashitaMasao Honda

Published in: Hepatology communications (2024)

Short-term l-carnitine administration ameliorated MASH through its anti-inflammatory effects. Long-term l-carnitine administration potentially improved the steatosis and fibrosis of MASH and may eventually reduce the risk of HCC.

Keyphrases

insulin resistance
oxidative stress
high fat diet
liver fibrosis
type diabetes
risk assessment
high fat diet induced