The oft-overlooked cardiovascular complications of inflammatory bowel disease.
Sara MassironiGiacomo MulinacciCamilla GalloChiara ViganòMaria FicheraAndrea VillatoreGiovanni PerettoSilvio DanesePublished in: Expert review of clinical immunology (2023)
CVD risk is slightly increased in patients with IBD, especially during flares. Thromboprophylaxis is strongly recommended in hospitalized patients with active disease as the benefit of anticoagulation outweighs the risk of bleeding. The pathogenetic relationship between CVD and IBD and the impact of IBD drugs on CVD outcomes are not fully elucidated. CVD risk doesn't have the strength to drive a specific IBD treatment. However, proper CVD risk profiling should always be done and the best strategy to manage CVD risk in IBD patients is to combine appropriate thromboprophylaxis with early and durable remission of the underlying IBD.