A liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based assay to profile 20 plasma steroids in endocrine disorders.

Zhenxin WangHao WangYingfei PengFangjun ChenLin ZhaoXiao-Mu LiJiaqian QinQianqian LiBeili WangBaishen PanWei Guo

Published in: Clinical chemistry and laboratory medicine (2020)

The LC-MS/MS method we developed for the quantification of 20 plasma steroids is clinical practicable. The steroid profiling data using this assay indicate its screening value for endocrine disorders. To further explore the value of the assay, more investigations are however needed.

Keyphrases

liquid chromatography tandem mass spectrometry
high throughput
simultaneous determination
ms ms
solid phase extraction
single cell
machine learning
high resolution