Age and gender effects on striatal dopamine transporter density and cerebral perfusion in individuals with non-degenerative parkinsonism: a dual-phase 18 F-FP-CIT PET study.
Ji-Young KimSeo Young KangByung Seok MoonBom Sahn KimJee Hyang JeongHai Jeon YoonPublished in: EJNMMI research (2024)
F-FP-CIT PET with a single injection, we demonstrate a negative impact of age on SBRs (DAT binding) in the striatum for both genders and SUVRs (cerebral perfusion) in the dorsal striatum and caudate nucleus for both genders and in the ventral striatum and putamen for males. Additionally, we found positive associations between SBR and SUVR values in the dorsal striatum, caudate nucleus, and putamen for both genders and in the ventral striatum for males.
Keyphrases
- prefrontal cortex
- spinal cord
- neuropathic pain
- subarachnoid hemorrhage
- computed tomography
- parkinson disease
- pet ct
- positron emission tomography
- deep brain stimulation
- contrast enhanced
- mental health
- cerebral ischemia
- spinal cord injury
- functional connectivity
- brain injury
- magnetic resonance imaging
- transcription factor
- drug induced