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NAT10 Is Involved in Cardiac Remodeling Through ac4C-Mediated Transcriptomic Regulation.

Jing ShiChuanxi YangKun ZhaoJing ZhangPeng LiChuiyu KongXiaoguang WuHao-Liang SunRui ZhengWei SunLianmin ChenXiang-Qing Kong
Published in: Circulation research (2023)
Therefore, our data suggest that modulating epitranscriptomic processes, such as ac4C acetylation through NAT10, may be a promising therapeutic target against cardiac remodeling.
Keyphrases
  • left ventricular
  • electronic health record
  • signaling pathway
  • single cell
  • big data
  • rna seq
  • heart failure
  • atrial fibrillation
  • histone deacetylase
  • data analysis