Peripapillary comet lesions and comet rain in PXE-related retinopathy.
Vittoria MurroDario Pasquale MuccioloAndrea SodiFederica BoraldiDaniela QuaglinoGianni VirgiliStanislao RizzoPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2018)
The comet lesion formation process involves the outer layers of the retina and RPE/Bruch's membrane complex. It consists of a degenerative/rearrangement process of the photoreceptors which occurs in an area of focal altered RPE/Bruch's membrane resembling the outer retinal tubulation.