Detection of NDM Variants ( bla NDM-1 , bla NDM-2 , bla NDM-3 ) from Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae : First Report from Nepal.

Anisha ThapaMilan Kumar UpretiNabin Kishor BimaliBasudha ShresthaAnil Kumar SahKrishus NepalBinod DhungelSanjib AdhikariNabaraj AdhikariBinod LekhakKomal Raj Rijal

Published in: Infection and drug resistance (2022)

Presence of NDM genes among carbapenemase-producing isolates is indicative of potential spread of drug-resistant variants. This study recommends the implementation of molecular diagnostic facilities in clinical settings for proper infection control, which can optimize the treatment therapies, and curb the emergence and spread of drug-resistant pathogens.

Keyphrases

klebsiella pneumoniae
drug resistant
multidrug resistant
gram negative
acinetobacter baumannii
escherichia coli
copy number
healthcare
primary care
gene expression
dna methylation
risk assessment
tertiary care
combination therapy
quality improvement
label free
sensitive detection
real time pcr