Consequences of not-shaking and shake-fire delays on the emitted dose of some commercial solution and suspension pressurized metered dose inhalers.
Veronica ChiericiLuca CavalieriAlessio PirainoDavide PaleariEride QuartaFabio SonvicoAndrea S MelaniFrancesca ButtiniPublished in: Expert opinion on drug delivery (2020)
The drug delivered can vary widely for no-shaking and over different shake-fire delays with suspension pMDIs while solution formulations appear to remain stable.
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