Associations of osteoprotegerin (OPG) TNFRSF11B gene polymorphisms with risk of fractures in older adult populations: meta-analysis of genetic and genome-wide association studies.

P TharabenjasinNoel PabalanH JarjanaziN Jinawath

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2021)

Evidence showed that the OPG (TNFRSF11B) polymorphisms reduced the risk for fracture in older adults, particularly protective among postmenopausal women, ≥ 60 y and Western subjects.

Keyphrases

postmenopausal women
genome wide association
bone mineral density
physical activity
south africa
genome wide
nuclear factor
community dwelling
middle aged
case control
gene expression
hip fracture
body composition
childhood cancer