MOFs@POMs-derived bimetallic oxide Fe 2 (MoO 4 ) 3 nanoparticles for sensitive colorimetric detection of salicylic acid in aspirin.
Hong HanYuhan JiXin ZhaoLing YinXiangyi LiuJing-Quan ShaPublished in: Mikrochimica acta (2024)
A colorimetric sensing method for salicylic acid (SA) was developed by designing and fabricating bimetallic oxide nanozymes. Firstly, by calcinating MIL-100(Fe)@PMo 12 (MOFs@POMs) at different temperature, Fe 2 (MoO 4 ) 3 -Ts (T = 400℃, 500℃, 600℃, 700℃) nanoparticles (NPs) were successfully prepared. Secondly, by evaluating the peroxidase-like activities, Fe 2 (MoO 4 ) 3 -600 NPs shows the best peroxidase-like activity attributed to the Fenton-like effect and the synergistic coupling interaction between Mo and Fe. Finally, based on the specific complexation between SA and Fe 3+ , a sensitive colorimetric sensor for SA was established, which exhibits superior selectivity and interference with a detection limit of 0.11 μM and a linear range of 10 to 100 μM, the lowest LOD for SA to date, to the best of our knowledge.
Keyphrases
- metal organic framework
- hydrogen peroxide
- aqueous solution
- gold nanoparticles
- sensitive detection
- label free
- low dose
- fluorescent probe
- nitric oxide
- loop mediated isothermal amplification
- coronary artery disease
- type diabetes
- room temperature
- drug delivery
- antiplatelet therapy
- cancer therapy
- cardiovascular events
- percutaneous coronary intervention
- neural network