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The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin Aging.

Feng QinJiuzuo HuangWenchao ZhangMingzi ZhangZhenjiang LiLoubin SiXiao LongXiao-Jun Wang
Published in: Stem cells international (2020)
ASCs improved the function of both UVB-damaged and healthy HDFs through paracrine effects. However, the impact of ASCs on healthy HDFs was greater than UVB-damaged HDFs. These findings help to elucidate the underlying mechanisms of the skin rejuvenation effect of ASCs.
Keyphrases
  • wound healing
  • soft tissue
  • high glucose
  • diabetic rats
  • oxidative stress
  • endothelial cells
  • platelet rich plasma