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Airway microbiome, host immune response and recurrent wheezing in infants with severe respiratory syncytial virus bronchiolitis.

Xiaoyan ZhangXiang ZhangNan ZhangXinglan WangLin SunNing ChenShunying ZhaoQiushui He
Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2020)
Our study suggests that higher abundance of Haemophilus and Moraxella in airway microbiome might modulate airway inflammation during severe RSV bronchiolitis in infancy, potentially contributing to the development of subsequent recurrent wheezing in later childhood.
Keyphrases
  • respiratory syncytial virus
  • immune response
  • early onset
  • toll like receptor