Clinical Implications and Molecular Features of Extracellular Matrix Networks in Soft Tissue Sarcomas.
Valeriya PankovaLukas KrasnyWilliam KerrisonYuen Bun TamMadhumeeta ChadhaJessica BurnsChristopher P WildingLiang ChenAvirup ChowdhuryEmma PerkinsAlexander T J LeeLouise HowellNafia GuljarKaren SisleyCyril FisherPriya ChudasamaKhin ThwayRobin L JonesPaul H HuangPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
STS comprise heterogeneous ECM signaling networks and matrix-specific features that have utility for risk stratification and therapy selection, which could in future guide precision medicine in these rare cancers.