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Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs.

Shabana N ASaleem Ullah ShahidShahida Hasnain
Published in: Lipids in health and disease (2018)
In conclusion, the use of gene score is a better way to calculate the overall genetic risk from common variants rather than individual risk variants.
Keyphrases
  • copy number
  • genome wide
  • dna methylation
  • type diabetes
  • insulin resistance
  • weight loss
  • gene expression
  • adipose tissue
  • skeletal muscle