Natural History, Phenotype Spectrum and Clinical Outcomes of Desmin ( DES )-Associated Cardiomyopathy.

Babken AsatryanMarina RiederBrittney Murray Steven A MullerCrystal TichnellAlessio GasperettiRichard T CarrickEmily JosephDoris G LeungAnneline S J M Te Riele Stefan L Zimmerman Hugh Calkins Cynthia A James Andreas S Barth

Published in: medRxiv : the preprint server for health sciences (2024)

cardiomyopathy exhibits heterogeneous phenotypes and distinct natural history, characterized by high familial penetrance and substantial MACE burden. Male patients face higher risk of sustained VA events.

Keyphrases

end stage renal disease
heart failure
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
patient reported outcomes