Polymeric Nanoparticles-Based Brain Delivery with Improved Therapeutic Efficacy of Ginkgolide B in Parkinson's Disease.

Yuying ZhaoSha XiongPiaoxue LiuWei LiuQun WangYao LiuHanxu TanXiao-Jia ChenXuguang ShiQi WangTongkai Chen

Published in: International journal of nanomedicine (2020)

In conclusion, these results indicate that NPs encapsulation of GB can significantly improve its oral bioavailability, cerebral accumulation, and bioactivity via mediating its sustained release in vivo.

Keyphrases

cerebral ischemia
drug delivery
subarachnoid hemorrhage
resting state
white matter
cancer therapy
functional connectivity
drug release
brain injury
multiple sclerosis
blood brain barrier