Statistical recommendations for count, binary, and ordinal data in rare disease cross-over trials.

Martin GeroldingerJohan VerbeeckAndrew C HookerKonstantin E ThielGeert MolenberghsJoakim NybergJohann BauerMartin LaimerVerena WallyArne C BathkeGeorg Zimmermann

Published in: Orphanet journal of rare diseases (2023)

Overall, a balance has to be found between achieving high power, accounting for cross-over, period, or carry-over effects, and prioritizing clinically relevant time points.

Keyphrases

electronic health record
big data
ionic liquid
peripheral blood
artificial intelligence
data analysis