Bone Marrow-Derived CD44+ Cells Migrate to Tissue-Engineered Constructs via SDF-1/CXCR4-JNK Pathway and Aid Bone Repair.

Yanzhu LuJunchao XingXiaolong YinXiaobo ZhuAijun YangJiyue LuoJing GouShiwu Dong Jianzhong Xu Tianyong Hou

Published in: Stem cells international (2019)

Together, we demonstrated that during bone repair promoted by TECs, BM-derived CD44+ cells were essential and their migration towards TECs could be regulated by the SDF-1/CXCR4-JNK signaling pathway.

Keyphrases

induced apoptosis
signaling pathway
endoplasmic reticulum stress
cell cycle arrest
cell death
pi k akt
oxidative stress
bone mineral density
epithelial mesenchymal transition
soft tissue
bone regeneration
bone loss
cell proliferation
postmenopausal women