Impaired left ventricular systolic synchrony in patients with lupus Nephritis: A speckle tracking echocardiography study.
Wei HePeihan XieWei LiFengjuan YaoYanqiu LiuLiuqin LiangDonghong LiuPublished in: Lupus (2022)
Patients with LN have more severe myocardial involvement than patients with extra-renal SLE. The asynchrony in myocardial contraction represented by the LVMD can be recognized earlier than that of the overall contractile functional impairment represented by GLS. In patients with LN, the 24-hour proteinuria was associated with LVMD. This indicates that the heterogeneity in the contractile function may be associated with the severity of renal damage.
Keyphrases
- left ventricular
- hypertrophic cardiomyopathy
- smooth muscle
- heart failure
- cardiac resynchronization therapy
- acute myocardial infarction
- skeletal muscle
- aortic stenosis
- left atrial
- mitral valve
- systemic lupus erythematosus
- blood pressure
- oxidative stress
- single cell
- disease activity
- rheumatoid arthritis
- coronary artery disease