Combination of Paclitaxel and MG1 oncolytic virus as a successful strategy for breast cancer treatment.
Marie-Claude Bourgeois-DaigneaultLauren Elizabeth St-GermainDominic Guy RoyAdrian PelinAmelia Sadie AitkenRozanne ArulanandamTheresa FallsVanessa GarciaJean-Simon DialloJohn Cameron BellPublished in: Breast cancer research : BCR (2016)
The combination of MG1 and Paclitaxel improved efficacy in all of the breast cancer models we tested and thus is a promising alternative approach for the treatment of patients with refractory breast cancer. Our strategy has potential for rapid translation to the clinic, given the current clinical status of both agents.