Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and P-tau231.

Sherif BayoumyInge M W VerberkBen den DulkZulaiga HussainaliMarissa ZwanWiesje M van der FlierNicholas J AshtonHenrik ZetterbergKaj BlennowJeroen VanbrabantErik StoopsEugeen VanmechelenJeffrey L DageCharlotte E Teunissen

Published in: Alzheimer's research & therapy (2021)

P-tau isoforms can be measured robustly by several novel high-sensitive Simoa assays.

Keyphrases

cerebrospinal fluid
high throughput
mass spectrometry