Mast Cells Regulate Ductular Reaction and Intestinal Inflammation in Cholestasis Through Farnesoid X Receptor Signaling.

Vik MeadowsLindsey KennedyBurcin EkserKonstantina KyritsiDebjyoti KunduTianhao ZhouLixian ChenLinh PhamNan WuJennifer DemievilleLaura HargroveShannon GlaserGianfranco AlpiniHeather Francis

Published in: Hepatology (Baltimore, Md.) (2021)

Our studies demonstrate that MC-FXR plays a key role in liver damage and DR, including TBA regulation through alteration of intestinal and biliary FXR/FGF15 signaling.

Keyphrases

oxidative stress
drug induced
editorial comment
electron transfer