Liver transplant-free survival according to alkaline phosphatase and GLOBE score in patients with primary biliary cholangitis treated with ursodeoxycholic acid.
Adriaan J van der MeerMaren H HarmsChristophe CorpechotDouglas ThorburnInvernizzi PietroHarry L A JanssenPier M BattezzatiFrederik NevensKeith D LindorAnnarosa FloreaniCyriel Y PonsioenMarlyn J MayoAlbert ParésAndrew L MasonKris V KowdleyPalak J TrivediGideon M HirschfieldKaren SchmidtGeorge N DalekosNikolaos K GatselisXavier P D M J VerhelstWillem J LammersBettina E HansenHenk R van BuurenAdriaan J van der Meernull nullPublished in: Alimentary pharmacology & therapeutics (2022)
The LT-free survival of patients with PBC with a normal GLOBE score is optimal in case of normal ALP levels, also in relation to the general population. Despite their generally favourable prognosis, an elevated ALP level may still indicate a need for add-on therapy.