Login / Signup

Traditional Chinese Medicine Alleviates Ulcerative Colitis via Modulating Gut Microbiota.

Wan FengLei ZhuHong Shen
Published in: Evidence-based complementary and alternative medicine : eCAM (2022)
Ulcerative colitis (UC) is a chronic inflammatory bowel disorder characterized by relapsing and remitting inflammation of the bowel. In recent decades, traditional Chinese medicine (TCM) has been widely used in the therapy of UC. However, its underlying mechanisms have not been sufficiently elucidated. Accumulating studies indicate that the gut microbial dysbiosis is closely related to UC. It has been demonstrated that TCM could alter the composition of intestinal microbiota by enriching beneficial and SCFA-producing bacteria and reducing pathogenic bacteria. In this review, we discussed recent evidence regarding the TCM and its role in modulating gut microbiota for the treatment of UC.
Keyphrases
  • ulcerative colitis
  • multiple sclerosis
  • oxidative stress
  • signaling pathway
  • disease activity
  • stem cells
  • mouse model
  • systemic lupus erythematosus
  • mesenchymal stem cells
  • bone marrow
  • cell therapy