Brønsted acid/visible-light-promoted Markovnikov hydroamination of vinylarenes with arylamines.

Jiao GuiHaisheng XieFengjuan ChenZhipeng LiuXiao-Qi ZhangFubin JiangWei Zeng

Published in: Organic & biomolecular chemistry (2020)

A Brønsted acid/visible-light-promoted Markovnikov hydroamination of vinylarenes with arylamines in the presence of TPT and CF3CO2H has been developed. This transformation provides a green approach to alpha-amino-substituted arylalkanes under metal-free conditions.

Keyphrases

visible light
cystic fibrosis
molecular docking