Calprotectin impairs platelet survival in patients with primary antiphospholipid syndrome.
Claire K HoySomanathapura K NaveenKumarSherwin A NavazKavya SugurSrilakshmi YalavarthiCyrus SaroshTristin SmithKatarína KmeťováEmily ChongNoah F PetersChristine E RysengaGary L NormanGabriel Figueroa-ParraDava NelsonJennifer GirardAsra Z AhmedJordan K SchaeferJohann E GudjonssonJ Michelle KahlenbergJacqueline A MadisonJason S KnightCynthia S CrowsonAli Duarte GarciaYu ZuoPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2024)
These data suggest that calprotectin has the potential to be a functional biomarker and a new therapeutic target for APS thrombocytopenia.