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Brief report: bidirectional association of core autism features and cognitive abilities in early childhood.

Kelsie McGowanDaniel BerendsKristelle HudryGiacomo VivantiCheryl DissanayakeCatherine A Bent
Published in: Journal of autism and developmental disorders (2022)
We explored associations among the core behavioural features and developmental/cognitive abilities of 155 autistic children, assessed between ages 13-67 months and again around 1-year later to understand predictive directionality. Bidirectional, cross-domain association was apparent, albeit with stronger direction of effect from earlier cognition to later autism features (than vice versa). Exploratory sub-domain analysis showed that early non-verbal developmental/cognitive abilities (only) predicted subsequent social- and restricted/repetitive autism features, whereas early social features (only) predicted both subsequent verbal and non-verbal abilities. Although observational study design precludes causal inference, these data support contemporary notions of the developmental interconnectedness of core autism presentation and associated abilities-that behavioural autism features may influence cognitive development, but are likely also influenced by an individuals' cognitive capacity.
Keyphrases
  • autism spectrum disorder
  • intellectual disability
  • working memory
  • healthcare
  • mental health
  • young adults
  • computed tomography
  • single cell
  • magnetic resonance
  • mild cognitive impairment
  • case report
  • big data