The role of NOTCH3 variants in Alzheimer's disease and subcortical vascular dementia in the Chinese population.
Lina GuoBin JiaoXinxin LiaoXuewen XiaoWeiwei ZhangZhenhua YuanXixi LiuLu ZhouXin WangYuan ZhuQijie YangJun-Ling WangBeisha TangLu ShenPublished in: CNS neuroscience & therapeutics (2021)
Our findings broaden the mutational spectrum of NOTCH3 and validate the pathogenic role of NOTCH3 mutations in SVaD, but do not support the notion that NOTCH3 variation influences the risk of AD.