Incremental value of HBcrAg to classify 1582 HBeAg-negative individuals in chronic infection without liver disease or hepatitis.
Maurizia Rossana BrunettoIvana CareyBenjamin MaasoumyCristina Marcos-FoschAndré BoonstraGian Paolo CavigliaAlessandro LoglioDaniela CavalloneCaroline ScholtesGabriele RiccoAntonina SmedileMar Riveiro-BarcielaFlorian van BoemmelAnnemiek van der EijkFabien ZoulimThomas BergMarkus CornbergPietro LamperticoKosh AgarwalMaria Buti FerretPublished in: Alimentary pharmacology & therapeutics (2021)
The HBcrAg assay showed high diagnostic performance in the accurate single-point identification of patients with HBeAg-negative CHB, independently of HBV genotype. This should prompt future prospective studies to confirm its diagnostic role in clinical practice.