The Impact of Midodrine Tapering Versus Nontapering Regimens on the Clinical Outcomes of Critically Ill Patients: A Retrospective Cohort Study.

Jawaher GramishAhmed HattanOhoud AljuhaniP J ParameaswariShaden AlshehriGhazwa B KorayemHadeel AlkofideMai AlalawiRamesh VishwakarmaYazed Saleh AlsowaidaRahaf AlqahtaniLuluh BinorayirMohammed AbutalebAlanoud AlotaibiMajidah AljohaniSarah AljohaniSana SamreenSuad JawhariRaghad AlanaziKhalid Al Sulaiman

Published in: The Annals of pharmacotherapy (2023)

These real-life data showed that tapering midodrine dosage before discontinuation in critically ill patients during weaning from vasopressor aids in reducing the frequency of inotrope or vasopressor re-initiation. Application of such a strategy might be a reasonable approach among ICU patients unless contraindicated.

Keyphrases

end stage renal disease
mechanical ventilation
ejection fraction
peritoneal dialysis
newly diagnosed
intensive care unit
prognostic factors
electronic health record
patient reported outcomes
machine learning
data analysis