Vaccine-Associated Disease Enhancement (VADE): Considerations in Postvaccination COVID-19.

Rahajeng N Tunjungputri Erpryta Nurdia TetrasiwiMerlinda VeronicaJacub PandelakiFera IbrahimErni Juwita Nelwan

Published in: Case reports in medicine (2021)

We report two cases of patients developing COVID-19 shortly after CoronaVac vaccination in which VADE is likely. We recommend that current vaccination strategies consider the measurement of neutralizing antibody titer as a guide in ensuring the safest strategy for mass immunization. Studies are needed to investigate the true incidence of VADE on vaccinated individuals as well as on how to differentiate between VADE and severe manifestations of COVID-19 that are unrelated to vaccination.

Keyphrases

coronavirus disease
sars cov
end stage renal disease
ejection fraction
newly diagnosed
respiratory syndrome coronavirus
peritoneal dialysis
early onset
dengue virus