Impact of cytokine storm on severity of COVID-19 disease in a private hospital in West Jakarta prior to vaccination.
Diana Laila RamatillahSiew Hua GanIka PratiwySyed Azhar Syed SulaimanAmmar Ali Saleh JaberNina JusnitaStefanus LukasUsman Abu BakarPublished in: PloS one (2022)
Factors influencing the development of a cytokine storm include age, duration of treatment, comorbidity, symptoms, type of admission ward and severity of infection. Most patients (76.92%) with cytokine storm who received Gammaraas®/Actemra®, survived although they were in the severe and critical levels (87.17%). Overall, based on the treatment duration and survival rate, the most effective therapy was a combination of oseltamivir + favipiravir + hydroxychloroquine + antibiotics + vitamins/minerals.