Performance of multiplex serology in discriminating active vs past Helicobacter pylori infection in a primarily African American population in the southeastern United States.
Julia ButtWilliam J BlotMartha J ShrubsoleMatthew G VargaLaura H HendrixSydnee CrankshawTim WaterboerMichael PawlitaMeira EppleinPublished in: Helicobacter (2019)
Utilizing the cutoffs for seropositivity established through comparison with UBT, seropositivity to ≥2 of the H. pylori proteins VacA, GroEl, HcpC, and HP1564 determines active H. pylori infection at high specificity and sensitivity and may approximate the prevalence of active H. pylori infection in large cohorts.