Thrombolysis for acute ischemic stroke in the unwitnessed or extended therapeutic time window.
Georgios TsivgoulisAristeidis H KatsanosKonark MalhotraAmrou SarrajAndrew D BarretoMartin KöhrmannChristos KrogiasNiaz AhmedValeria CasoPeter D SchellingerAndrei V AlexandrovPublished in: Neurology (2019)
IVT in patients with AIS with unknown symptom onset time or elapsed time from symptom onset >4.5 hours selected with advanced neuroimaging results in a higher likelihood of CR and functional improvement at 3 months despite the increased risk of sICH.