Increased malaria parasitaemia among adults living with HIV who have discontinued cotrimoxazole prophylaxis in Kitgum district, Uganda.
Philip OrishabaJoan N KalyangoPauline Byakika-KibwikaEmmanuel ArinaitweBonnie WanderaThomas KatairoWani MuzeyiHildah Tendo NansikombiAlice NakatoTobius MutabaziMoses R KamyaGrant DorseyJoaniter I NankabirwaPublished in: PloS one (2020)
People from malaria endemic settings living with HIV have a higher prevalence of malaria parasitaemia following discontinuation of CTX compared to those still on prophylaxis. The risk increased with increasing duration since discontinuation of the prophylaxis. HIV patients should not discontinue CTX prophylaxis in areas of Uganda where the burden of malaria remains high. Other proven malaria control interventions may also be encouraged in HIV patients following discontinuation of CTX prophylaxis.