Novel Long Noncoding RNA HEAT4 Affects Monocyte Subtypes, Reducing Inflammation and Promoting Vascular Healing.

Jasmin Marga KneuerIgnacy A GrajekMelanie WinklerStephan ErbeTim MeineckeRonald WeissTania Garfias-Veitl Bilal N Sheikh Ann-Christine König Maximilian N Möbius-Winkler Alexander Kogel Karl-Patrik Kresoja Sebastian Rosch Karoline Elizabeth Kokot Vanina Filipova Susanne Gaul Holger Thiele Philipp Lurz Stephan von Haehling Thimoteus Speer Ulrich Laufs Jes-Niels Boeckel

Published in: Circulation (2024)

monocytes. The data identify a novel function for the class of long noncoding RNAs by preventing protein secretion and suggest long noncoding RNAs as potential targets for interventions in the field of cardioimmunology.

Keyphrases

long noncoding rna
dendritic cells
oxidative stress
peripheral blood
physical activity
electronic health record
big data
heat stress
endothelial cells
human health
protein protein
amino acid
risk assessment
immune response
small molecule
artificial intelligence