Login / Signup

Alcohol consumption, cigarette smoking, and familial breast cancer risk: findings from the Prospective Family Study Cohort (ProF-SC).

Nur ZeinomarJulia A KnightJeanine M GenkingerKelly-Anne PhillipsMary B DalyRoger L MilneGillian S DiteRebecca D KehmYuyan LiaoMelissa C SoutheyWendy K ChungGraham G GilesSue-Anne McLachlanMichael L FriedlanderPrue C WeidemanGord GlendonStephanie Nescinull nullIrene L AndrulisSaundra S BuysEsther M JohnRobert J MacInnisJohn L HopperMary Beth Terry
Published in: Breast cancer research : BCR (2019)
Moderate alcohol intake was associated with increased BC risk, particularly for women with ER-positive BC, but only for those at lower predicted familial BC risk (5-year BOADICEA < 1.25). For women with a high FRP (5-year BOADICEA ≥ 6.5%) who also consumed alcohol, being a current smoker was associated with increased BC risk.
Keyphrases
  • alcohol consumption
  • breast cancer risk
  • physical activity
  • body mass index
  • estrogen receptor
  • weight gain
  • endoplasmic reticulum