Nanomechanical properties of enucleated cells: contribution of the nucleus to the passive cell mechanics.

Yuri M EfremovSvetlana L KotovaAnastasia A AkovantsevaPeter S Timashev

Published in: Journal of nanobiotechnology (2020)

The cell can maintain its mechanical properties without the nucleus. Together, the obtained data indicate the dominating role of the actomyosin cytoskeleton over the nucleus in the cell mechanics at small deformations inflicted by AFM.

Keyphrases

single cell
cell therapy
stem cells
cell proliferation
bone marrow
cell death
cell cycle arrest
machine learning