Versatile ion S5XL sequencer for targeted next generation sequencing of solid tumors in a clinical laboratory.
Meenakshi MehrotraDzifa Yawa DuoseRajesh R SinghBedia A BarkohJawad ManekiaMichael A HarmonKeyur P PatelMark J RoutbortL Jeffrey MedeirosIgnacio I WistubaRajyalakshmi LuthraPublished in: PloS one (2017)
Ion S5XL system simplified workflow in a clinical laboratory, was feasible for running smaller and larger panels on the same instrument, had a shorter turnaround time, and showed good concordance for variant calls with similar sensitivity and reproducibility as the Ion PGM and Proton.