Co-stimulation of LPAR1 and S1PR1/3 increases the transplantation efficacy of human mesenchymal stem cells in drug-induced and alcoholic liver diseases.

Mianhuan LiYi LvFeng ChenXiaoyan WangJiang ZhuHao LiJia Xiao

Published in: Stem cell research & therapy (2018)

Co-use of LPA and S1P represents a novel and safe strategy to enhance stem cell transplantation efficacy for future drug- and alcoholic-related liver disease therapies.

Keyphrases

drug induced
liver injury
stem cell transplantation
mesenchymal stem cells
high dose
endothelial cells
adverse drug
umbilical cord
bone marrow
current status
stem cells
induced pluripotent stem cells
emergency department
low dose