Digital droplet PCR TERT promoter mutational screening in fine needle aspiration cytology of thyroid lesions: A highly specific technique for pre-operative identification of high-risk cases.
Martin HysekL Samuel HellgrenAdam StenmanEva Darai-RamqvistElin LjungIgor SchliemannVincenzo CondelloCatharina LarssonJan ZedeniusKenbugul JattaCarl Christofer JuhlinPublished in: Diagnostic cytopathology (2023)
In the present cohort, we found that ddPCR is a highly specific method for detecting high-risk TERT promoter mutations on thyroid FNAC material that could guide different surgical approaches in subsets of indeterminate lesions if reproduced in larger materials.