NHC-catalyzed [4 + 2] annulations of allenoates and 2,3-dioxopyrrolidine derivatives.

Xue SongYangxu ChenFangfang LuKai ZhangChenxia YuTuanjie LiChang-Sheng Yao

Published in: Organic & biomolecular chemistry (2022)

A facile NHC-catalyzed [2 + 4] annulation of allenoates with 2,3-dioxypyrrolidine derivatives was discovered, which paved a new avenue for the construction of highly substituted pyranopyrrole with moderate to good yields, high atom economy and mild reaction conditions.

Keyphrases

room temperature
structure activity relationship
molecular docking
molecular dynamics
high intensity
quantum dots
electron transfer
metal organic framework
gold nanoparticles