Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinoma.

Jiangqiao ZhouTianyu WangTao QiuZhongbao ChenXiaoxiong MaLong ZhangJilin Zou

Published in: BMC cancer (2020)

USP44 may be a marker in predicting ccRCC progression. Inhibition by USP44 of the proliferation and migration of 786-O cells and Caki-1 cells is dependent upon the JNK pathway.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
signaling pathway
cell death
oxidative stress
small molecule
cell proliferation