Connectivity Profile for Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease.
Mallory L HackerNanditha RajamaniClemens NeudorferBarbara HollunderSimon OxenfordNingfei LiAlice L SternbergThomas L DavisPeter E KonradAndreas HornDavid CharlesPublished in: Annals of neurology (2023)
These results suggest that stimulating the dorsolateral region of the STN receiving input from M1 and SMA (but not pre-SMA) is associated with slower motor progression across subjects receiving STN-DBS in early-stage PD. This finding is hypothesis-generating and must be prospectively tested in a larger prospective study. This article is protected by copyright. All rights reserved.
Keyphrases
- deep brain stimulation
- early stage
- parkinson disease
- obsessive compulsive disorder
- sentinel lymph node
- prefrontal cortex
- working memory
- resting state
- transcranial magnetic stimulation
- functional connectivity
- transcranial direct current stimulation
- white matter
- squamous cell carcinoma
- high frequency
- multiple sclerosis
- rectal cancer