Icaritin Sensitizes Thrombin- and TxA2-Induced Platelet Activation and Promotes Hemostasis via Enhancing PLCγ2-PKC Signaling Pathways.

Zhixiang ZhuYanggan LuoHanjing LiaoRan GuoDoudou HaoZihan LuManjing HuangChenghong SunJingchun YaoNing WeiKewu ZengPengfei TuGuimin Zhang

Published in: Thrombosis and haemostasis (2024)

through enhancing the activation of PLCγ2-PKC signaling pathways and promote hemostasis, and has potential to be developed into a novel orally deliverable therapeutic agent for hemorrhages.

Keyphrases

signaling pathway
induced apoptosis
pi k akt
diabetic rats
high glucose
epithelial mesenchymal transition
protein kinase
oxidative stress
risk assessment
drug induced
human health
climate change