Extract of white sweet potato tuber against TNF-α-induced insulin resistance by activating the PI3K/Akt pathway in C2C12 myotubes.
Lie-Fen ShyurViola VargaChiao-Ming ChenShu-Chi MuYu-Chih ChangSing-Chung LiPublished in: Botanical studies (2021)
WSP-EA enhanced the glucose uptake in C2C12 myotubes through upregulating the PI3K/Akt pathway. The in vitro data reveal that WSP tuber extracts has potential applications to improve insulin resistance in diabetes.
Keyphrases
- insulin resistance
- type diabetes
- glycemic control
- diabetic rats
- cardiovascular disease
- high glucose
- oxidative stress
- rheumatoid arthritis
- adipose tissue
- signaling pathway
- metabolic syndrome
- electronic health record
- blood glucose
- genome wide
- polycystic ovary syndrome
- high fat diet
- single cell
- drug induced
- human health
- high fat diet induced
- machine learning
- blood pressure
- climate change
- risk assessment
- artificial intelligence
- weight loss
- deep learning