Cytokine Receptor-like Factor 1 (CRLF1) and Its Role in Osteochondral Repair.

Fenglin Zhang Andrew J ClairJohn F DankertYou Jin LeeKirk A CampbellThorsten Kirsch

Published in: Cells (2024)

A homodimeric CRLF1 complex released by BMSCs enhanced the repair of osteochondral defects via the inhibition of catabolic events in chondrocytes and the stimulation of chondrogenic differentiation of precursor cells.

Keyphrases

induced apoptosis
cell cycle arrest
platelet rich plasma
mesenchymal stem cells
endoplasmic reticulum stress
cell death
signaling pathway