In vitro activity of antimicrobial-impregnated catheters against biofilms formed by KPC-producing Klebsiella pneumoniae.
J K T de SousaJoão Paulo Amaral HaddadAdriana Cristina de OliveiraCristina Dutra VieiraSimone Gonçalves Dos SantosPublished in: Journal of applied microbiology (2019)
Our results highlighted that the in vitro efficacy of antimicrobial-impregnated CVCs is limited by time and that their colonization occurred earlier than expected. Our data also demonstrated that NAC/LEV remained active until day 30 of evaluation and CHX/SS combination was completely inactivated from day 15 on. Our findings suggested that implantable devices should be carefully used by medical community.