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Cancer in Systemic Sclerosis: Analysis of Antibodies Against Components of the Th/To Complex.

Christopher A MecoliBrittany L AdlerQingyuan YangLaura K HummersAntony RosenLivia A Casciola-RosenChristopher A Mecoli
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
SSc patients who produce autoantibodies to components of the Th/To complex have a clinical phenotype characterized by limited cutaneous disease and pulmonary involvement. Our findings show that the presence of any Th/To autoantibody may have a protective effect against contemporaneous cancer.
Keyphrases
  • systemic sclerosis
  • papillary thyroid
  • interstitial lung disease
  • squamous cell
  • pulmonary hypertension
  • squamous cell carcinoma
  • rheumatoid arthritis