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The role of the mucosa in modulation of evoked responses in the spinal cord injured rat bladder.

Claire DoyleVivian CristofaroBryan S SackFabliha MahmoodMaryrose P SullivanRosalyn M Adam
Published in: Neurourology and urodynamics (2018)
Detrusor-mucosa interactions are substantially altered in the neurogenic bladder. After spinal cord injury, an excitatory modulation of smooth muscle contraction by the mucosa emerges, and could be targeted via intravesical treatment in the context of neurogenic bladder dysfunction.
Keyphrases
  • spinal cord injury
  • smooth muscle
  • spinal cord
  • neuropathic pain
  • urinary tract
  • oxidative stress
  • cancer therapy
  • combination therapy
  • drug delivery
  • botulinum toxin
  • replacement therapy